Lipid droplet-free nanovesicles extruded from stromal vascular fraction improve adipocyte regeneration in the centre of dermal graft
These findings revealed that extruding SVF into nanovesicles can effectively reduce the implantation of lipid droplets that cause inflammation, and co-transplanting SVF-EVs with dermal microparticles may be a considerable strategy for large volume defects repair.
Authors
- Jiaming Sun (ORCID: https://orcid.org/0000-0003-4973-6636)
- Ran An (ORCID: https://orcid.org/0000-0002-4849-0120)
- Rongrong Wang (ORCID: https://orcid.org/0000-0002-5084-977X)
- Jie Yang (ORCID: https://orcid.org/0000-0003-3720-3808)
- Di Sun (ORCID: https://orcid.org/0009-0007-3968-0612)
- Yuyang Zeng (ORCID: https://orcid.org/0000-0003-4048-5199)
Institutions
- Union Hospital (HK)
- Tongji Hospital (CN)
- Huazhong University of Science and Technology (CN)
Publication Details
- Journal
- Stem Cell Research & Therapy
- Published
- 2025-03-05
- DOI
- https://doi.org/10.1186/s13287-025-04240-6
- Primary Topic
- Extracellular vesicles in disease
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Key Research and Development Program of China