Lipid Dysregulation in Tangier Disease: A Case Series and Metabolic Characterization

Clinical phenotypes of TD can be heterogeneous including gastrointestinal and neurological manifestations. Impaired triglyceride-rich lipoprotein clearance and hepatic lipase activity could be a pathophysiological hallmark of TD.

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Publication Details

Journal
The Journal of Clinical Endocrinology & Metabolism
Published
2025-02-27
DOI
https://doi.org/10.1210/clinem/dgaf131
Citations
3
Primary Topic
Peroxisome Proliferator-Activated Receptors
Type
article
Field-Weighted Citation Impact
2.42
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article

Lipid Dysregulation in Tangier Disease: A Case Series and Metabolic Characterization

Winfried März, Elmar Aigner, Hansjörg Habisch, Harald Esterbauer et al.
3 citations
The Journal of Clinical Endocrinology & Metabolism
Peroxisome Proliferator-Activated Receptors
2.42
article

Lipid Dysregulation in Tangier Disease: A Case Series and Metabolic Characterization

Winfried März, Elmar Aigner, Hansjörg Habisch, Harald Esterbauer, Bernhard Wernly, Thomas Scherer, Susanne Greber‐Platzer, Sophie Gensluckner, Matthäus Metz, Christian Datz, Tobias Madl, Andreas Völkerer, Georg Semmler, Oleksandr Petrenko, Hannah Hofer, Clemens Baumgartner, Felix Offner, Manuela Neyer, Sophie Draxler-Dworzak, Charlotte Nigmann
article en
3 citations

Abstract

Clinical phenotypes of TD can be heterogeneous including gastrointestinal and neurological manifestations. Impaired triglyceride-rich lipoprotein clearance and hepatic lipase activity could be a pathophysiological hallmark of TD.

The Journal of Clinical Endocrinology & MetabolismVol. 110(7)
University of Southern Denmark (DK), Medical University of Graz (AT), Heidelberg University (DE), Paracelsus Medical University (AT), Odense University Hospital (DK), University Hospital Heidelberg (DE), Landeskrankenhaus Feldkirch (AT), Max Planck Institute for Metabolism Research (DE), BioTechMed-Graz (AT), Krankenhaus Oberndorf (AT), Synlab (Germany) (DE), Vorarlberg Institute for Vascular Investigation and Treatment (AT), University Medical Centre Mannheim (DE), Research Institute of Ukrainian Studies (UA), Medical University of Vienna (AT)
Good health and well-being
Openalex Percentile: Top 13%
Peroxisome Proliferator-Activated Receptors
2.42
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