Catalyst-Free Radical Dearomatization of Phenols with Aryldiazonium Tetrafluoroborates and DABCO·(SO2)2
Abstract A catalyst-free, three-component dearomatization of phenols with aryldiazonium tetrafluoroborates and DABCO·(SO2)2 has been developed for the synthesis of 4-(arylsulfonyl)cyclohex-2,5-dien-1-one scaffolds. This method offers mild reaction conditions and high step efficiency, providing a green and efficient strategy for the dearomatization of phenols. Mechanistic studies indicated that this transformation relies on a tandem radical sulfur dioxide insertion process.
Authors
- Guanyinsheng Qiu (ORCID: https://orcid.org/0000-0002-6587-8522)
- Xingxian Zhang (ORCID: https://orcid.org/0000-0003-4474-7600)
- Chenchen Cai (ORCID: https://orcid.org/0000-0002-6706-1460)
- Guang Cheng (ORCID: https://orcid.org/0000-0002-6860-4420)
- Shaoyu Li
Institutions
- Zhejiang University of Technology (CN)
- Taizhou University (CN)
Publication Details
- Journal
- Synlett
- Published
- 2025-03-04
- DOI
- https://doi.org/10.1055/s-0043-1773522
- Citations
- 2
- Primary Topic
- Sulfur-Based Synthesis Techniques
- Type
- article
- Field-Weighted Citation Impact
- 1.87
Funders
- National Natural Science Foundation of China
- Science and Technology Plan Project of Taizhou
- Natural Science Foundation of Zhejiang Province