A human-infecting H10N5 avian influenza virus: Clinical features, virus reassortment, receptor-binding affinity, and possible transmission routes
Unlike the human-infecting H10N3 and H10N8 AIVs acquiring six internal protein-coding genes from H9N2 AIVs in domestic poultry, the human-infecting H10N5 AIV was generated through multiple reassortments among viruses mainly carried by wild Anseriformes. Furthermore, worldwide distribution, inter-continental transmission, and genetic exchanges between Eurasian and North American lineages call for more concerns about influenza surveillance on H10Ny AIVs, especially in the flyway overlapping areas.
Authors
- Ju Sun (ORCID: https://orcid.org/0000-0002-2017-5903)
- Yuhai Bi (ORCID: https://orcid.org/0000-0002-5595-363X)
- Haibo Wu (ORCID: https://orcid.org/0000-0001-5550-5186)
- Zhigang Wu (ORCID: https://orcid.org/0000-0002-6931-6498)
- Lanjuan Li (ORCID: https://orcid.org/0000-0001-6945-0593)
- Hangping Yao (ORCID: https://orcid.org/0000-0001-6742-7074)
- Shufa Zheng (ORCID: https://orcid.org/0000-0003-2536-1008)
- Tian Tian (ORCID: https://orcid.org/0000-0002-5466-676X)
- Dan Zhang (ORCID: https://orcid.org/0000-0002-1111-1721)
- Jing Yang (ORCID: https://orcid.org/0000-0002-2457-3634)
- Linwei Zhu
- Yanjun Wang (ORCID: https://orcid.org/0000-0001-6121-8706)
Institutions
- Shanghai Institute of Nutrition and Health (CN)
- Institute of Microbiology (CN)
- Early Warning (United States) (US)
- University of Chinese Academy of Sciences (CN)
- First Affiliated Hospital Zhejiang University (CN)
- State Key Laboratory of Diagnosis and Treatment of Infectious Diseases
- Zhejiang University (CN)
Publication Details
- Journal
- Journal of Infection
- Published
- 2025-03-04
- DOI
- https://doi.org/10.1016/j.jinf.2025.106456
- Citations
- 17
- Primary Topic
- Influenza Virus Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 23.02
Funders
- National Natural Science Foundation of China
- Fundamental Research Funds for the Central Universities