2025 European guideline on the management of <i>Chlamydia trachomatis</i> infections

Sexually transmitted <i>Chlamydia trachomatis</i> infections remain common globally and most frequently are asymptomatic. The 2025 European <i>C. trachomatis</i> guideline provides up-to-date guidance regarding indications for testing and treatment of <i>C. trachomatis</i> infections. It includes advice on urogenital and extragenital <i>C. trachomatis</i> testing including the use of self-collected specimens; recommendation to use only validated NAATs for diagnosis; and recommendation to treat all <i>C. trachomatis</i> infections with doxycycline as first line in preference to single-dose azithromycin regimens. The absence of evidence and limited value of broad screening in asymptomatic populations for <i>C. trachomatis</i> infections is also discussed.

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Publication Details

Journal
International Journal of STD & AIDS
Published
2025-03-04
DOI
https://doi.org/10.1177/09564624251323678
Citations
25
Primary Topic
Reproductive tract infections research
Type
article
Field-Weighted Citation Impact
29.58
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article

2025 European guideline on the management of Chlamydia trachomatis infections

Nicole H. T. M. Dukers–Muijrers, John Albert White, Jonathan Ross, Chris Kenyon et al.
25 citations
International Journal of STD & AIDS
Reproductive tract infections research
29.58
article

2025 European guideline on the management of Chlamydia trachomatis infections

Nicole H. T. M. Dukers–Muijrers, John Albert White, Jonathan Ross, Chris Kenyon, Magnus Unemo, Christian J. P. A. Hoebe
article en
25 citations

Abstract

Sexually transmitted <i>Chlamydia trachomatis</i> infections remain common globally and most frequently are asymptomatic. The 2025 European <i>C. trachomatis</i> guideline provides up-to-date guidance regarding indications for testing and treatment of <i>C. trachomatis</i> infections. It includes advice on urogenital and extragenital <i>C. trachomatis</i> testing including the use of self-collected specimens; recommendation to use only validated NAATs for diagnosis; and recommendation to treat all <i>C. trachomatis</i> infections with doxycycline as first line in preference to single-dose azithromycin regimens. The absence of evidence and limited value of broad screening in asymptomatic populations for <i>C. trachomatis</i> infections is also discussed.

International Journal of STD & AIDSVol. 36(6)
University Hospitals Birmingham NHS Foundation Trust (GB), Örebro University (SE), Maastricht University Medical Centre (NL), Maastricht University (NL), Western Health and Social Care Trust (GB), GGD Zuid Limburg (NL), University College London (GB), Instituut voor Tropische Geneeskunde (BE)
Good health and well-being
Openalex Percentile: Top 0%
Reproductive tract infections research
29.58
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2025 European guideline on the management of <i>Chlamydia trachomatis</i> infections — Nicole H. T. M. Dukers–Muijrers, John Albert White, et al. · International Journal of STD & AIDS (2025) | TGRS Research Map | TGRS