Long-term results of locoregionally advanced nasopharyngeal carcinoma treated with cisplatin and 5-fluorouracil induction chemotherapy with or without docetaxel in young and middle aged adults
PF and TPF followed by radiotherapy with or without concurrent chemotherapy performed encouraging anti-tumor effects in LA-NPC, there was no statistical significance in 5-year and 8-year OS, RRFS, and DMFS rates between two chemotherapy regimens. Compared with PF, TPF induction chemotherapy achieved more satisfactory LRFS rate in LA-NPC with acceptable toxicity.
Authors
- Dan Ou (ORCID: https://orcid.org/0000-0001-9485-6042)
- Xiaoshuang Niu (ORCID: https://orcid.org/0000-0001-6286-411X)
- Chaosu Hu (ORCID: https://orcid.org/0000-0001-6407-3311)
- Xiayun He (ORCID: https://orcid.org/0000-0002-1652-3012)
- Yuming Zheng
- Fen Xue (ORCID: https://orcid.org/0009-0002-3361-1206)
Institutions
- Shanghai Medical College of Fudan University (CN)
- Fudan University Shanghai Cancer Center (CN)
- Shanghai Clinical Research Center (CN)
Publication Details
- Journal
- Journal of Cancer Research and Clinical Oncology
- Published
- 2025-03-04
- DOI
- https://doi.org/10.1007/s00432-025-06145-6
- Citations
- 2
- Primary Topic
- Head and Neck Cancer Studies
- Type
- article
- Field-Weighted Citation Impact
- 3.70
Funders
- Scientific and Innovative Action Plan of Shanghai