Current Approaches to the Management of Postoperative Fistulas in Gastric Cancer Surgery: Experience of a Tertiary Center

<b>Background:</b> Gastric cancer remains a leading global health challenge, despite advances in surgical techniques and perioperative care. Patients with gastric cancer present with a degree of postoperative complications, most notably anastomotic fistulas, which can lead to a high level of morbidity and mortality. Although significant advances have been made in their management by implementing less invasive methods, issues and debate remain regarding their early detection and treatment decisions. The purpose of this study was to emphasize the particularities of the treatment of postoperative fistulas in gastric cancer surgery, focusing on risk factors as well as management strategies. <b>Methods:</b> This retrospective study analyzed risk factors, diagnostic methods, and treatment strategies for anastomotic fistulas in 527 patients undergoing curative gastric cancer surgery over the span of five years, highlighting postoperative complication rates, the management of postoperative complications, and the primary risk factors for developing fistulas. <b>Results:</b> Conservative treatment combined with minimally invasive interventions achieved a primary success rate of over 65%, with surgical intervention being reserved for severe cases. The primary risk factors identified were an advanced tumor stage, total gastrectomy, type II diabetes mellitus, and a high number of transfusions required, as well as hypoalbuminemia. <b>Conclusions:</b> Although further research is required to standardize treatment protocols and reduce the morbidity and mortality associated with postoperative fistulas, understanding the primary elements of its causation can prove helpful in choosing the correct treatment.

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Publication Details

Journal
Journal of Clinical Medicine
Published
2025-03-04
DOI
https://doi.org/10.3390/jcm14051733
Citations
2
Primary Topic
Gastric Cancer Management and Outcomes
Type
article
Field-Weighted Citation Impact
3.04
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article

Current Approaches to the Management of Postoperative Fistulas in Gastric Cancer Surgery: Experience of a Tertiary Center

Nadim Al Hajjar, Alin Fetti, Dan Vălean, Roxana Zaharie et al.
2 citations
Journal of Clinical Medicine
Gastric Cancer Management and Outcomes
3.04
article

Current Approaches to the Management of Postoperative Fistulas in Gastric Cancer Surgery: Experience of a Tertiary Center

Nadim Al Hajjar, Alin Fetti, Dan Vălean, Roxana Zaharie, Florin Zaharie, Vlad-Ionuț Nechita, Vlad Radu Puia, Roman Țăulean, Ioan Cătălin Bodea, Oana Moșincat
article en
2 citations

Abstract

<b>Background:</b> Gastric cancer remains a leading global health challenge, despite advances in surgical techniques and perioperative care. Patients with gastric cancer present with a degree of postoperative complications, most notably anastomotic fistulas, which can lead to a high level of morbidity and mortality. Although significant advances have been made in their management by implementing less invasive methods, issues and debate remain regarding their early detection and treatment decisions. The purpose of this study was to emphasize the particularities of the treatment of postoperative fistulas in gastric cancer surgery, focusing on risk factors as well as management strategies. <b>Methods:</b> This retrospective study analyzed risk factors, diagnostic methods, and treatment strategies for anastomotic fistulas in 527 patients undergoing curative gastric cancer surgery over the span of five years, highlighting postoperative complication rates, the management of postoperative complications, and the primary risk factors for developing fistulas. <b>Results:</b> Conservative treatment combined with minimally invasive interventions achieved a primary success rate of over 65%, with surgical intervention being reserved for severe cases. The primary risk factors identified were an advanced tumor stage, total gastrectomy, type II diabetes mellitus, and a high number of transfusions required, as well as hypoalbuminemia. <b>Conclusions:</b> Although further research is required to standardize treatment protocols and reduce the morbidity and mortality associated with postoperative fistulas, understanding the primary elements of its causation can prove helpful in choosing the correct treatment.

Journal of Clinical MedicineVol. 14(5)
Iuliu Hațieganu University of Medicine and Pharmacy (RO), Institutul Regional de Gastroenterologie Prof. Dr. Octavian Fodor (RO)
Good health and well-being
Openalex Percentile: Top 11%
Gastric Cancer Management and Outcomes
3.04
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