Untargeted Metabolomics and Chemometrics Elucidate Dynamic Plasma Profile Changes Induced by Cocoa Shell in Female Rats
The observed metabolic reconfiguration demonstrates CSE's rapid modulation of the metabolome, highlighting the bioavailability of its key components. These findings suggest potential mechanisms for CSE as a functional food ingredient with health-promoting effects, potentially supporting cognitive function and metabolic health through energy metabolism, neurotransmission, and lipid signaling pathways.
Authors
- Pilar Rodríguez‐Rodríguez (ORCID: https://orcid.org/0000-0002-6483-8289)
- Miguel Rebollo‐Hernanz (ORCID: https://orcid.org/0000-0003-1034-1290)
- María Á. Martín-Cabrejas (ORCID: https://orcid.org/0000-0001-9834-639X)
- David Ramiro‐Cortijo (ORCID: https://orcid.org/0000-0001-7442-1586)
- Santiago Ruvira (ORCID: https://orcid.org/0000-0003-2216-5335)
- Silvia M. Arribas (ORCID: https://orcid.org/0000-0001-7103-6105)
Institutions
- Instituto de Investigación en Ciencias de la Alimentación (ES)
- Universidad Autónoma de Madrid (ES)
Publication Details
- Journal
- Nutrients
- Published
- 2025-02-28
- DOI
- https://doi.org/10.3390/nu17050885
- Citations
- 1
- Primary Topic
- Biochemical effects in animals
- Type
- article
- Field-Weighted Citation Impact
- 1.16
Funders
- Ministerio de Ciencia e Innovación