Eculizumab as a Disease‐Modifying Therapy in Chronic Inflammatory Demyelinating Polyneuropathy (<scp>CIDP</scp>): A Case Report

CIDP pathogenesis is characterized by a complex interplay of different immunopathological mechanisms, and the complement system may play a major role. The present case supports the role of complement-dependent toxicity in CIDP and suggests that complement-targeted therapies may represent a well-tolerated and effective alternative for CIDP treatment.

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Publication Details

Journal
Journal of the Peripheral Nervous System
Published
2025-03-01
DOI
https://doi.org/10.1111/jns.70010
Citations
3
Primary Topic
Peripheral Neuropathies and Disorders
Type
article
Field-Weighted Citation Impact
4.17
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article

Eculizumab as a Disease‐Modifying Therapy in Chronic Inflammatory Demyelinating Polyneuropathy (CIDP): A Case Report

Letizia Bertolasi, Michela Ripolone, Carlo Ferrarese, L. Marzorati et al.
3 citations
Journal of the Peripheral Nervous System
Peripheral Neuropathies and Disorders
4.17
article

Eculizumab as a Disease‐Modifying Therapy in Chronic Inflammatory Demyelinating Polyneuropathy (CIDP): A Case Report

Letizia Bertolasi, Michela Ripolone, Carlo Ferrarese, L. Marzorati, Maria Letizia Fusco, M. Frigo, Edoardo Dalmato Schilke, Claudia Balducci, Diletta Cereda, Lorenzo Stanzani, Guido Cavaletti, Nico Farina, Franco Molteni
article en
3 citations

Abstract

CIDP pathogenesis is characterized by a complex interplay of different immunopathological mechanisms, and the complement system may play a major role. The present case supports the role of complement-dependent toxicity in CIDP and suggests that complement-targeted therapies may represent a well-tolerated and effective alternative for CIDP treatment.

Journal of the Peripheral Nervous SystemVol. 30(1)
Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico (IT), Azienda Ospedaliera San Gerardo (IT), Ospedale Valduce (IT), University of Milano-Bicocca (IT)
Reduced inequalities
Openalex Percentile: Top 7%
Peripheral Neuropathies and Disorders
4.17
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