Electron Microscopic Findings Predict Clinical Outcomes in Patients with Non-Ischaemic Cardiomyopathy
Discontinuous nuclear envelopes were associated with a reduced LVRR rate, whereas injured myofilaments were correlated with higher 1 year cardiac events and a decreased LVRR. Evaluation of electron microscopic images in diagnostic endomyocardial biopsy can facilitate risk stratification of NICM or DCM with reduced EF.
Authors
- Hiroyuki Takahama (ORCID: https://orcid.org/0000-0003-4155-1936)
- Yoshihiko Ikeda
- Tomohito Ohtani (ORCID: https://orcid.org/0000-0002-2963-7895)
- Masaru Hatano (ORCID: https://orcid.org/0000-0003-2135-3625)
- Machiko Kanzaki
- Shozo Konishi (ORCID: https://orcid.org/0000-0001-6458-2685)
- Fusako Sera
- Toyoaki Murohara (ORCID: https://orcid.org/0000-0003-2723-6243)
- Misato Chimura (ORCID: https://orcid.org/0000-0003-3674-9171)
- Yoshihiro Asano (ORCID: https://orcid.org/0000-0002-5972-739X)
- Yasushi Sakata (ORCID: https://orcid.org/0000-0002-5618-4721)
- Issei Komuro (ORCID: https://orcid.org/0000-0002-0714-7182)
- Hatsue Ishibashi‐Ueda (ORCID: https://orcid.org/0000-0001-5153-9805)
- Atsushi Okada (ORCID: https://orcid.org/0000-0002-0087-4168)
- Takahiro Okumura (ORCID: https://orcid.org/0000-0001-5076-2052)
- Rie Higuchi
- Themistoklis Katsimichas
- Chisato Izumi (ORCID: https://orcid.org/0000-0002-3282-1327)
- Masahiro Seo (ORCID: https://orcid.org/0000-0001-6517-486X)
- T Watanabe
Institutions
- Tohoku University (JP)
- Osaka Prefectural Medical Center (JP)
- Osaka City General Hospital (JP)
- National Cerebral and Cardiovascular Center (JP)
- Takatsuki General Hospital (JP)
- Hippocration General Hospital (GR)
- Nagoya University (JP)
- The University of Tokyo (JP)
- International University of Health and Welfare (JP)
- The University of Osaka (JP)
Publication Details
- Journal
- ESC Heart Failure
- Published
- 2025-03-02
- DOI
- https://doi.org/10.1002/ehf2.15255
- Primary Topic
- Cardiomyopathy and Myosin Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Japan Agency for Medical Research and Development