Emerging role of IGF1R and IR expression and localisation in adrenocortical carcinomas
Overall, these data suggest that IGF1R localisation and IR expression represent new biomarkers predicting tumour aggressiveness, as well as possible molecular markers useful to patients' stratification for more individualized IGF1R-IR targeted therapies or for novel pharmacological approaches specifically targeting IRA isoform.
Authors
- Ludovica Baldari (ORCID: https://orcid.org/0000-0002-7029-8485)
- Mariangela Tamburello (ORCID: https://orcid.org/0000-0001-7827-0025)
- Michaela Luconi (ORCID: https://orcid.org/0000-0001-5186-064X)
- Guido Di Dalmazi (ORCID: https://orcid.org/0000-0002-1291-8906)
- Donatella Treppiedi (ORCID: https://orcid.org/0000-0001-6636-2619)
- Cristina L. Ronchi (ORCID: https://orcid.org/0000-0001-5020-2071)
- Giorgio Alberto Croci (ORCID: https://orcid.org/0000-0001-5979-7841)
- Barbara Altieri (ORCID: https://orcid.org/0000-0003-2616-3249)
- Giovanna Mantovani (ORCID: https://orcid.org/0000-0002-9065-3886)
- Serena Palmieri (ORCID: https://orcid.org/0000-0002-1137-461X)
- Sandra Sigala (ORCID: https://orcid.org/0000-0003-3294-4121)
- Alessandra Mangone (ORCID: https://orcid.org/0000-0003-1035-8551)
- Constanze Hantel (ORCID: https://orcid.org/0009-0000-8906-2563)
- Mario Detomas (ORCID: https://orcid.org/0000-0001-7864-6125)
- Laura‐Sophie Landwehr (ORCID: https://orcid.org/0000-0002-6315-4176)
- Marc Philipp Schauer
- Erika Peverelli (ORCID: https://orcid.org/0000-0002-4424-7895)
- Emanuela Esposito (ORCID: https://orcid.org/0000-0002-9238-0367)
- Emma Nozza (ORCID: https://orcid.org/0000-0002-1573-036X)
- Otilia Kimpel (ORCID: https://orcid.org/0000-0002-8283-7861)
- Letizia Canu (ORCID: https://orcid.org/0000-0003-4995-8108)
- Anna G. Angelousi (ORCID: https://orcid.org/0000-0003-0906-3617)
- Rosa Catalano (ORCID: https://orcid.org/0000-0001-6260-3489)
- Emanuele Ferrante (ORCID: https://orcid.org/0000-0002-0556-7650)
- Elisa Cassinotti (ORCID: https://orcid.org/0000-0003-3780-6561)
- Gabriella Nesi (ORCID: https://orcid.org/0000-0002-2614-944X)
- Anna Maria Barbieri (ORCID: https://orcid.org/0000-0003-4909-7512)
- Sonia Di Bari
- Sabine Herterich
Institutions
- National Technical University of Athens (GR)
- University of Milan (IT)
- National and Kapodistrian University of Athens (GR)
- University of Zurich (CH)
- University of Würzburg (DE)
- Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico (IT)
- University Hospital of Zurich (CH)
- Laiko General Hospital of Athens (GR)
- Azienda Ospedaliero-Universitaria Careggi (IT)
- Azienda USL di Bologna (IT)
- Universitätsklinikum Würzburg (DE)
- University Hospital Carl Gustav Carus (DE)
- University of Florence (IT)
- University of Birmingham (GB)
- University of Brescia (IT)
- University of Bologna (IT)
Publication Details
- Journal
- Cell Communication and Signaling
- Published
- 2025-03-04
- DOI
- https://doi.org/10.1186/s12964-025-02115-0
- Citations
- 3
- Primary Topic
- Adrenal and Paraganglionic Tumors
- Type
- article
- Field-Weighted Citation Impact
- 6.02
Funders
- Ministero della Salute