Abnormal arm swing movements in Parkinson’s disease: onset, progression and response to L-Dopa
Arm swing movements during gait in PD are characterized by narrow, slow, and irregular patterns. As the disease progresses, arm swing movements deteriorate also in the less affected hemibody, without any joint specificity. The positive response to L-Dopa along with the significant correlation between kinematics and bradykinesia/rigidity scores points to the involvement of dopaminergic pathways in the pathophysiology of abnormal arm swing movements in PD.
Authors
- Giovanni Saggio (ORCID: https://orcid.org/0000-0002-9034-9921)
- Francesco Fattapposta (ORCID: https://orcid.org/0000-0003-4189-3792)
- Antonio Pisani (ORCID: https://orcid.org/0000-0002-8432-594X)
- Alessandro Zampogna (ORCID: https://orcid.org/0000-0002-0227-1993)
- Giulia Di Lazzaro (ORCID: https://orcid.org/0000-0003-2413-1788)
- Valeria Rosati
- Paolo Grillo (ORCID: https://orcid.org/0000-0002-4958-7178)
- Martina Patera (ORCID: https://orcid.org/0009-0000-8677-0468)
- Giovanni Costantini (ORCID: https://orcid.org/0000-0001-8675-5532)
- Marco Falletti (ORCID: https://orcid.org/0000-0001-9732-1414)
- Antonio Suppa (ORCID: https://orcid.org/0000-0001-9903-5550)
- F. Giannini (ORCID: https://orcid.org/0000-0003-0132-2522)
- Luca Pietrosanti
- Francesco Asci (ORCID: https://orcid.org/0000-0003-0717-3521)
- Elena Bianchini
- Giulia Pinola
Institutions
- University of Rome Tor Vergata (IT)
- University of Pavia (IT)
- Agostino Gemelli University Polyclinic (IT)
- Istituto Neurologico Mediterraneo (IT)
- Sapienza University of Rome (IT)
Publication Details
- Journal
- Journal of NeuroEngineering and Rehabilitation
- Published
- 2025-03-04
- DOI
- https://doi.org/10.1186/s12984-025-01589-w
- Citations
- 4
- Primary Topic
- Parkinson's Disease Mechanisms and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 5.56