Portal Vein Thrombosis in Second Trimester of Pregnancy

<b>Background:</b> Acute portal vein thrombosis can be asymptomatic or may present with non-specific symptoms, making awareness and vigilance crucial among pregnant patients. The management of portal vein thrombosis (PVT) diagnosed during pregnancy is not well defined, as most existing data relate to cases diagnosed before pregnancy. Symptoms can resemble other pregnancy-related conditions, posing a challenge for clinicians. PVT during pregnancy can be effectively and safely managed with anticoagulation therapy. However, the potential for complications necessitates a multidisciplinary approach. This article outlines the case of PVT in a 39-year-old woman in the 14th week of gestation who was admitted through the emergency department due to an acute onset of abdominal pain predominantly in the epigastric and right hypochondriac regions. <b>Methods:</b> Abdominal ultrasonography revealed PVT, and treatment with low-molecular-weight heparins was commenced. Further investigation excluded any form of thrombophilic state. <b>Results:</b> The patient continued an adjusted dosage of thrombolytics after discharge until the end of her pregnancy and was reinstated for thromboprophylaxis following a caesarean section. <b>Conclusions:</b> A thorough diagnosis is vital for any abdominal pain in pregnancy. A personalised approach is essential for effectively managing PVT, highlighting the need for early detection and comprehensive care to optimise outcomes for both the mother and the offspring.

Authors

Institutions

Publication Details

Journal
Journal of Clinical Medicine
Published
2025-03-04
DOI
https://doi.org/10.3390/jcm14051713
Citations
2
Primary Topic
Venous Thromboembolism Diagnosis and Management
Type
article
Field-Weighted Citation Impact
3.74
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Portal Vein Thrombosis in Second Trimester of Pregnancy

Michaela Jezberová, Katarína Gazdíková, Martina Slováčiková, Miroslava Dobrotová et al.
2 citations
Journal of Clinical Medicine
Venous Thromboembolism Diagnosis and Management
3.74
article

Portal Vein Thrombosis in Second Trimester of Pregnancy

Michaela Jezberová, Katarína Gazdíková, Martina Slováčiková, Miroslava Dobrotová, Miroslav Žigrai, Adriana Gregušová
article en
2 citations

Abstract

<b>Background:</b> Acute portal vein thrombosis can be asymptomatic or may present with non-specific symptoms, making awareness and vigilance crucial among pregnant patients. The management of portal vein thrombosis (PVT) diagnosed during pregnancy is not well defined, as most existing data relate to cases diagnosed before pregnancy. Symptoms can resemble other pregnancy-related conditions, posing a challenge for clinicians. PVT during pregnancy can be effectively and safely managed with anticoagulation therapy. However, the potential for complications necessitates a multidisciplinary approach. This article outlines the case of PVT in a 39-year-old woman in the 14th week of gestation who was admitted through the emergency department due to an acute onset of abdominal pain predominantly in the epigastric and right hypochondriac regions. <b>Methods:</b> Abdominal ultrasonography revealed PVT, and treatment with low-molecular-weight heparins was commenced. Further investigation excluded any form of thrombophilic state. <b>Results:</b> The patient continued an adjusted dosage of thrombolytics after discharge until the end of her pregnancy and was reinstated for thromboprophylaxis following a caesarean section. <b>Conclusions:</b> A thorough diagnosis is vital for any abdominal pain in pregnancy. A personalised approach is essential for effectively managing PVT, highlighting the need for early detection and comprehensive care to optimise outcomes for both the mother and the offspring.

Journal of Clinical MedicineVol. 14(5)
Slovak Medical University (SK), University Hospital Bratislava (SK), Comenius University Bratislava (SK)
Good health and well-being
Openalex Percentile: Top 9%
Venous Thromboembolism Diagnosis and Management
3.74
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.