Recovery of hypopituitarism in macroprolactinomas: a comparison of medical vs. surgical treatment. Results from a European multicenter study
Both surgical and medical treatment allow for hormonal recovery in patients with macroprolactinoma, with no significant advantage for either approach. Initial tumor size and prolactin-normalization are predictors of recovery outcomes.
Authors
- Timo Deutschbein (ORCID: https://orcid.org/0000-0003-0586-0168)
- Joerg Flitsch
- Martin Faßnacht (ORCID: https://orcid.org/0000-0001-6170-6398)
- Mario Detomas (ORCID: https://orcid.org/0000-0003-1490-5575)
- Barbara Altieri (ORCID: https://orcid.org/0000-0003-2616-3249)
- J. Honegger (ORCID: https://orcid.org/0000-0002-7249-8077)
- Marco Losa (ORCID: https://orcid.org/0000-0001-7810-8247)
- Isabella Nasi‐Kordhishti (ORCID: https://orcid.org/0000-0003-2226-4958)
- Francesco Chierigo (ORCID: https://orcid.org/0000-0001-7357-0758)
- Linus Haberbosch (ORCID: https://orcid.org/0000-0002-4464-0427)
- Alice Ryba (ORCID: https://orcid.org/0000-0002-0130-8838)
- Pietro Mortini (ORCID: https://orcid.org/0000-0003-2320-2281)
Institutions
- Vita-Salute San Raffaele University (IT)
- Queen Mary University of London (GB)
- University of Würzburg (DE)
- University Medical Center Hamburg-Eppendorf (DE)
- University Children's Hospital Tübingen (DE)
- Universitätsklinikum Würzburg (DE)
- Medicover (DE)
- William Harvey Research Institute (GB)
- Istituti di Ricovero e Cura a Carattere Scientifico (IT)
- Azienda Socio Sanitaria Territoriale Santi Paolo e Carlo
- Charité - Universitätsmedizin Berlin (DE)
Publication Details
- Journal
- Journal of Endocrinological Investigation
- Published
- 2025-03-04
- DOI
- https://doi.org/10.1007/s40618-025-02559-8
- Citations
- 4
- Primary Topic
- Pituitary Gland Disorders and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 5.18
Funders
- Deutsche Forschungsgemeinschaft