Disorders of Iron Metabolism: A “Sharp Edge” of Deoxynivalenol-Induced Hepatotoxicity
Based on our results, the Nrf2 pathway is closely associated with DON-induced iron metabolism disorders and ferroptosis in mouse livers, suggesting that maintaining hepatic iron homeostasis and activating the Nrf2 pathway may be a potential target for mitigating DON hepatotoxicity in the future.
Authors
- Yujing Cui
- Huidan Deng (ORCID: https://orcid.org/0000-0003-2301-8871)
- Junliang Deng (ORCID: https://orcid.org/0000-0002-7159-1923)
- Zichun Hua (ORCID: https://orcid.org/0000-0001-7962-0402)
- Youtian Deng
- Haoyue Guan (ORCID: https://orcid.org/0000-0002-6633-173X)
Institutions
- Sichuan Agricultural University (CN)
Publication Details
- Journal
- Metabolites
- Published
- 2025-03-01
- DOI
- https://doi.org/10.3390/metabo15030165
- Citations
- 4
- Primary Topic
- Glutathione Transferases and Polymorphisms
- Type
- article
- Field-Weighted Citation Impact
- 3.22
Funders
- National Natural Science Foundation of China