Pathomorphological changes of the placenta in pregnant women with the status of internally displaced persons

The objective: to evaluation of the role of pathological changes in the placenta in the development of pregnancy complications in patients with the status of internally displaced persons.Materials and methods. A retrospective analysis of the pathohistological study of placenta from 37 woman with the status of internally displaced persons who gave birth in the municipal non-profit enterprise “Kyiv City Maternity Hospital No. 2” in 2022–2023 was conducted.The study included pregnant women from 18 to 38 years old with a singleton pregnancy that occurred spontaneously, primigravida woman and multigravida women who were primaparous, the woman did not have severe somatic pathology and had the status of internally displaced persons. All women gave birth between 37 and 42 weeks of pregnancy.Data on the characteristics of the pregnancy course and its results obtained from the patients’ medical records were analyzed. Microscopic and macroscopic study of the placenta, pathohistological research of placental tissue were performed. Results. The average age of the examined women was 29.7 ± 0.86 years. As a result of the study, it was determined that the highest frequency of the detected pathologies was chorioamnionitis – 18 (51.4%) cases. The most common complication of pregnancy in women who were internally displaced persons, according to the study, was placental dysfunction – in 14 cases (40.5%). This confirms the importance of inflammatory changes in the placenta in the pathogenesis of the formation of placental dysfunction.Conclusions. Pathomorphological changes in the placentas of patients with the status of internally displaced persons reflected the main links in the pathogenesis of infectious and inflammatory processes. The study confirms the main role of the infectious factor in the structural and morphological changes of the placenta in pregnant women who are internally displaced persons.