Logistic Regression-based Approach for Gene Function Prediction

Gene function prediction is a critical task in bioinformatics, as it provides insights into the roles and interactions of genes within biological systems. The current research landscape is characterized by a variety of computational methods aimed at improving prediction accuracy. However, existing approaches often face challenges related to scalability and interpretability. In this paper, we propose a novel logistic regression-based approach that leverages gene expression data to predict gene functions more effectively. By incorporating expression profiles into the prediction model, our method offers improved accuracy and interpretability compared to traditional methods. Our experimental results demonstrate the efficacy of the proposed approach in accurately predicting gene functions, thus highlighting its potential to enhance our understanding of complex biological systems.

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Publication Details

Journal
Optimizations in Applied Machine Learning
Published
2025-02-27
DOI
https://doi.org/10.71070/oaml.v5i1.90
Primary Topic
Machine Learning in Bioinformatics
Type
article
Field-Weighted Citation Impact
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article

Logistic Regression-based Approach for Gene Function Prediction

Huang Jin-tai, Weiling Chen, Lin Mei-Yu
Optimizations in Applied Machine Learning
Machine Learning in Bioinformatics
article

Logistic Regression-based Approach for Gene Function Prediction

Huang Jin-tai, Weiling Chen, Lin Mei-Yu
article en

Abstract

Gene function prediction is a critical task in bioinformatics, as it provides insights into the roles and interactions of genes within biological systems. The current research landscape is characterized by a variety of computational methods aimed at improving prediction accuracy. However, existing approaches often face challenges related to scalability and interpretability. In this paper, we propose a novel logistic regression-based approach that leverages gene expression data to predict gene functions more effectively. By incorporating expression profiles into the prediction model, our method offers improved accuracy and interpretability compared to traditional methods. Our experimental results demonstrate the efficacy of the proposed approach in accurately predicting gene functions, thus highlighting its potential to enhance our understanding of complex biological systems.

Optimizations in Applied Machine LearningVol. 5(1)
National University of Tainan (TW), National Chiayi University (TW), National Ilan University (TW)
Openalex Percentile: Top 96%
Machine Learning in Bioinformatics
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Logistic Regression-based Approach for Gene Function Prediction — Huang Jin-tai, Weiling Chen, et al. · Optimizations in Applied Machine Learning (2025) | TGRS Research Map | TGRS