Advances in Tissue Engineering for the Treatment of Urethral Stricture

Urethral stricture is a common disease of the urinary system, mainly caused by trauma, inflammation, iatrogenic injury and other factors, which can lead to dysuria, urinary retention and even renal function impairment, seriously affecting the quality of life of patients. Traditional treatments such as urethral dilatation and urethroplasty have limitations, including a high recurrence rate, many complications, and a lack of graft. Recent rapid development in tissue engineering techniques has provided a new direction for the repair of urethral strictures. This review summarizes the progress of tissue engineering in the treatment of urethral strictures, including the application of scaffold materials, seed cells, bioactive factors, and explores the challenges and prospects of future development.