The role of ubiquitin C–terminal hydrolase (UCH‐L1) and protein <scp>S100B</scp> in differentiating patients with epileptic and psychogenic non‐epileptic seizures – Pilot study

This study evaluated two potential biomarkers, UCH-L1 and S100B, to differentiate ES from PNES in clinical practice. Our findings showed elevated postictal UCH-L1 levels in subjects with epilepsy compared to those with PNES, while no significant differences in S100B levels were observed among the groups.

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Publication Details

Journal
Epilepsia Open
Published
2025-03-02
DOI
https://doi.org/10.1002/epi4.13130
Primary Topic
Epilepsy research and treatment
Type
article
Field-Weighted Citation Impact
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article

The role of ubiquitin C–terminal hydrolase (UCH‐L1) and protein S100B in differentiating patients with epileptic and psychogenic non‐epileptic seizures – Pilot study

Željka Petelin Gadže, Maja Živković, Biljana Đapić Ivančić, Petra Nimac Kozina et al.
Epilepsia Open
Epilepsy research and treatment
article

The role of ubiquitin C–terminal hydrolase (UCH‐L1) and protein S100B in differentiating patients with epileptic and psychogenic non‐epileptic seizures – Pilot study

Željka Petelin Gadže, Maja Živković, Biljana Đapić Ivančić, Petra Nimac Kozina, Lana Ganoci, Dunja Rogić
article en

Abstract

This study evaluated two potential biomarkers, UCH-L1 and S100B, to differentiate ES from PNES in clinical practice. Our findings showed elevated postictal UCH-L1 levels in subjects with epilepsy compared to those with PNES, while no significant differences in S100B levels were observed among the groups.

Epilepsia OpenVol. 10(2)
University Hospital Centre Zagreb (HR), University of Zagreb (HR), Ministry of Health (HR)
Good health and well-being
Openalex Percentile: Top 95%
Epilepsy research and treatment
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