Analysis of LINC00472 as a biomarker of osteoarthritis and its clinical value
LINC00472 is involved in chondrocyte apoptosis, extracellular matrix degradation, and cellular inflammation in OA through the miR-361-5p/MECP2 axis. LINC00472 may regulate OA development by increasing MECP2 expression through sponged miR-361-5p and may be a new target for OA diagnosis and treatment.
Authors
- Zhibin Li
- Weijun Zhang (ORCID: https://orcid.org/0009-0009-9959-0840)
Institutions
- Xuzhou Medical College (CN)
- Xuzhou No.1 People's Hospital (CN)
Publication Details
- Journal
- Archives of Rheumatology
- Published
- 2024-12-31
- DOI
- https://doi.org/10.46497/archrheumatol.2024.10739
- Citations
- 1
- Primary Topic
- Cancer-related molecular mechanisms research
- Type
- article
- Field-Weighted Citation Impact
- 0.29
Funders
- Xuzhou Medical University