Embryonic heritage: a unique case of Wolffian duct tumor in a 75-year-old female patient Modern approaches to morphological diagnostics

Female adnexal tumor of Wolffian origin is an extremely rare and poorly studied tumor arising from remnants of Wolffian (mesonephric) duct and having an ambiguous malignancy potential. Immunohistochemical diagnostics of these tumors is important to exclude other pathologies. Interpretation of the prognosis is ambiguous. There are no clear standards for surgical or chemotherapeutic treatment. This is due to the lack of a sufficient number of observations and clinical studies. The article presents a clinical case of Wolffian duct tumor diagnosed in a 75-year-old patient, with a discussion of the terminological, morphological, immunohistochemical and molecular genetic features of the tumor.

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Publication Details

Journal
Tumors of female reproductive system
Published
2024-12-03
DOI
https://doi.org/10.17650/1994-4098-2024-20-4-139-147
Primary Topic
Tumors and Oncological Cases
Type
article
Field-Weighted Citation Impact
0.00
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article

Embryonic heritage: a unique case of Wolffian duct tumor in a 75-year-old female patient Modern approaches to morphological diagnostics

Sergey Vladimirovich Vtorushin, А. Б. Виллерт, М. О. Очиров, Л. А. Коломиец et al.
Tumors of female reproductive system
Tumors and Oncological Cases
article

Embryonic heritage: a unique case of Wolffian duct tumor in a 75-year-old female patient Modern approaches to morphological diagnostics

Sergey Vladimirovich Vtorushin, А. Б. Виллерт, М. О. Очиров, Л. А. Коломиец, A. A. Maltseva, O. A. Bondyreva, S. A. Villert
article en

Abstract

Female adnexal tumor of Wolffian origin is an extremely rare and poorly studied tumor arising from remnants of Wolffian (mesonephric) duct and having an ambiguous malignancy potential. Immunohistochemical diagnostics of these tumors is important to exclude other pathologies. Interpretation of the prognosis is ambiguous. There are no clear standards for surgical or chemotherapeutic treatment. This is due to the lack of a sufficient number of observations and clinical studies. The article presents a clinical case of Wolffian duct tumor diagnosed in a 75-year-old patient, with a discussion of the terminological, morphological, immunohistochemical and molecular genetic features of the tumor.

Tumors of female reproductive systemVol. 20(4)
Russian Academy of Sciences (RU), Siberian State Medical University (RU), Ministry of Health of the Russian Federation (RU), Tomsk National Research Medical Center (RU)
Openalex Percentile: Top 59%
Tumors and Oncological Cases
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Embryonic heritage: a unique case of Wolffian duct tumor in a 75-year-old female patient Modern approaches to morphological diagnostics — Sergey Vladimirovich Vtorushin, А. Б. Виллерт, et al. · Tumors of female reproductive system (2024) | TGRS Research Map | TGRS