Evaluation of possible sources of polymer embolization after fenestrated aortic repairs mimicking spinal cord ischemia
Hydrophilic polymer embolization (HPE) syndrome after fenestrated endovascular aortic repair is a rare and devastating complication. Currently, no data exist linking clinical HPE to specific candidate endovascular devices from which the polymer may have arisen. We report two cases of HPE in patients who underwent fenestrated endovascular aortic repairs. Using a dermal biopsy sample and 18 routinely used devices, scanning electron microscopy and energy dispersive x-ray spectroscopy established matches in elemental signature between the devices and embolized material located in dermal capillaries. Using a carbon to oxygen ratio of approximately 1.5, we identified eight devices with polymer material suspected to be the source of the embolization.
Authors
- Hillary Elwood
- Muhammad Ali Rana (ORCID: https://orcid.org/0000-0002-2937-1193)
- M. Rehman (ORCID: https://orcid.org/0000-0003-0538-8713)
- Ross Clark (ORCID: https://orcid.org/0000-0003-3712-8414)
- Pierce Massie (ORCID: https://orcid.org/0000-0003-3643-3791)
- Axel Zimmermann
- Kristin Markle
Institutions
- University of New Mexico (US)
- University of Virginia (US)
Publication Details
- Journal
- Journal of Vascular Surgery Cases and Innovative Techniques
- Published
- 2025-03-04
- DOI
- https://doi.org/10.1016/j.jvscit.2025.101765
- Citations
- 1
- Primary Topic
- Aortic Disease and Treatment Approaches
- Type
- article
- Field-Weighted Citation Impact
- 1.52
Funders
- National Center for Advancing Translational Sciences