Evaluation of possible sources of polymer embolization after fenestrated aortic repairs mimicking spinal cord ischemia

Hydrophilic polymer embolization (HPE) syndrome after fenestrated endovascular aortic repair is a rare and devastating complication. Currently, no data exist linking clinical HPE to specific candidate endovascular devices from which the polymer may have arisen. We report two cases of HPE in patients who underwent fenestrated endovascular aortic repairs. Using a dermal biopsy sample and 18 routinely used devices, scanning electron microscopy and energy dispersive x-ray spectroscopy established matches in elemental signature between the devices and embolized material located in dermal capillaries. Using a carbon to oxygen ratio of approximately 1.5, we identified eight devices with polymer material suspected to be the source of the embolization.

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Publication Details

Journal
Journal of Vascular Surgery Cases and Innovative Techniques
Published
2025-03-04
DOI
https://doi.org/10.1016/j.jvscit.2025.101765
Citations
1
Primary Topic
Aortic Disease and Treatment Approaches
Type
article
Field-Weighted Citation Impact
1.52

Funders

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article

Evaluation of possible sources of polymer embolization after fenestrated aortic repairs mimicking spinal cord ischemia

Hillary Elwood, Muhammad Ali Rana, M. Rehman, Ross Clark et al.
1 citations
Journal of Vascular Surgery Cases and Innovative Techniques
Aortic Disease and Treatment Approaches
1.52
article

Evaluation of possible sources of polymer embolization after fenestrated aortic repairs mimicking spinal cord ischemia

Hillary Elwood, Muhammad Ali Rana, M. Rehman, Ross Clark, Pierce Massie, Axel Zimmermann, Kristin Markle
article en
1 citations

Abstract

Hydrophilic polymer embolization (HPE) syndrome after fenestrated endovascular aortic repair is a rare and devastating complication. Currently, no data exist linking clinical HPE to specific candidate endovascular devices from which the polymer may have arisen. We report two cases of HPE in patients who underwent fenestrated endovascular aortic repairs. Using a dermal biopsy sample and 18 routinely used devices, scanning electron microscopy and energy dispersive x-ray spectroscopy established matches in elemental signature between the devices and embolized material located in dermal capillaries. Using a carbon to oxygen ratio of approximately 1.5, we identified eight devices with polymer material suspected to be the source of the embolization.

Journal of Vascular Surgery Cases and Innovative TechniquesVol. 11(3)
University of New Mexico (US), University of Virginia (US)
National Center for Advancing Translational Sciences
Openalex Percentile: Top 21%
Aortic Disease and Treatment Approaches
1.52
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