Assessing non-invasive quantitative methods for [18F]SynVesT-1 PET imaging of synaptic vesicle glycoprotein 2A in the rat brain

These findings validate kinetic modelling methods for [<sup>18</sup>F]SynVesT-1 PET, enabling their application in further rat studies for preclinical neuroscience research and prove that image-derived input functions are reliable non-invasive alternatives to AIF.

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Publication Details

Journal
European Journal of Nuclear Medicine and Molecular Imaging
Published
2025-03-04
DOI
https://doi.org/10.1007/s00259-025-07170-w
Citations
3
Primary Topic
Medical Imaging Techniques and Applications
Type
article
Field-Weighted Citation Impact
4.08

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article

Assessing non-invasive quantitative methods for [18F]SynVesT-1 PET imaging of synaptic vesicle glycoprotein 2A in the rat brain

Alan Miranda, Daniele Bertoglio, Steven Staelens, Claudia Schrauwen et al.
3 citations
European Journal of Nuclear Medicine and Molecular Imaging
Medical Imaging Techniques and Applications
4.08
article

Assessing non-invasive quantitative methods for [18F]SynVesT-1 PET imaging of synaptic vesicle glycoprotein 2A in the rat brain

Alan Miranda, Daniele Bertoglio, Steven Staelens, Claudia Schrauwen, Lori Berckmans
article en
3 citations

Abstract

These findings validate kinetic modelling methods for [<sup>18</sup>F]SynVesT-1 PET, enabling their application in further rat studies for preclinical neuroscience research and prove that image-derived input functions are reliable non-invasive alternatives to AIF.

European Journal of Nuclear Medicine and Molecular ImagingVol. 52(9)
University of Antwerp (BE), University of Namur (BE)
Wings for Life, Queen Elisabeth Medical Foundation, Fonds Wetenschappelijk Onderzoek
Zero hunger
Openalex Percentile: Top 7%
Medical Imaging Techniques and Applications
4.08
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