Alternations in morphometric similarity network in mesial temporal epilepsy correlate to neuroinflammatory pathway gene transcriptions
These findings suggest that brain-wide macroscopic morphometric alternations in mTLE are correlated to the neuroinflammation process. It provides circumstantial evidence from a new perspective to support the bidirectional link between mTLE and neurodegenerative diseases.
Authors
- Dongmei An (ORCID: https://orcid.org/0000-0003-4622-0837)
- Jinpeng Niu (ORCID: https://orcid.org/0000-0002-6448-6615)
- Josemir W. A. S. Sander (ORCID: https://orcid.org/0000-0001-6041-9661)
- Lu Lu (ORCID: https://orcid.org/0000-0002-7700-1939)
- Xintong Wu (ORCID: https://orcid.org/0000-0002-7676-3288)
- Dong Chi Zhou (ORCID: https://orcid.org/0000-0001-7101-4125)
- Qiyong Gong (ORCID: https://orcid.org/0000-0002-5912-4871)
- Bo Wang (ORCID: https://orcid.org/0000-0002-3231-1167)
- Wei Liao (ORCID: https://orcid.org/0000-0001-7406-7193)
- Yaohui He (ORCID: https://orcid.org/0000-0002-8235-8924)
- Yingying Zhang (ORCID: https://orcid.org/0009-0003-2520-0674)
- Hesheng Zhang (ORCID: https://orcid.org/0000-0001-9780-7422)
- Wei Li (ORCID: https://orcid.org/0009-0005-9530-2689)
- Ping Jiang (ORCID: https://orcid.org/0000-0001-9953-6443)
- Lin Chen (ORCID: https://orcid.org/0000-0002-2290-1630)
- Peiyu Wang (ORCID: https://orcid.org/0000-0003-2824-6443)
- Chenyang Zhao (ORCID: https://orcid.org/0009-0005-8692-2915)
- Keping Chen
- Yi Lü (ORCID: https://orcid.org/0000-0001-7832-3019)
- Yu Zhao (ORCID: https://orcid.org/0000-0003-4000-9387)
- Wei‐Hao Liao (ORCID: https://orcid.org/0009-0000-0167-5470)
Institutions
- University of Electronic Science and Technology of China (CN)
- Chinese Academy of Sciences (CN)
- Sichuan University (CN)
- West China Hospital of Sichuan University (CN)
- Institute of Biophysics (CN)
- National Hospital for Neurology and Neurosurgery (GB)
- Shanghai Center for Brain Science and Brain-Inspired Technology (CN)
- University College London (GB)
Publication Details
- Journal
- Acta Epileptologica
- Published
- 2025-03-04
- DOI
- https://doi.org/10.1186/s42494-025-00208-4
- Citations
- 1
- Primary Topic
- Epilepsy research and treatment
- Type
- article
- Field-Weighted Citation Impact
- 1.47