Serotonin regulates in a cell-type specific manner light-evoked response and synaptic activity in mouse retinal ganglion cells
Altogether these findings indicate that 5-HT modulates excitatory inputs onto RGCs in a cell-type specific manner and highlight that in the adult mouse retina, 5-HT-mediated effects onto RGCs are tightly controlled by the 5-HT transporter SERT.
Authors
- Sebastián F. Estay (ORCID: https://orcid.org/0000-0001-8114-023X)
- Alejandro Alcaino (ORCID: https://orcid.org/0009-0006-7876-5662)
- Claudia Di Berardino (ORCID: https://orcid.org/0009-0008-4834-0529)
- Andrés E. Chávez (ORCID: https://orcid.org/0000-0001-8795-9238)
Institutions
- Vita-Salute San Raffaele University (IT)
- Istituti di Ricovero e Cura a Carattere Scientifico (IT)
- Istituto di Ricovero e Cura a Carattere Scientifico San Raffaele (IT)
- University of Valparaíso (CL)
Publication Details
- Journal
- Biological Research
- Published
- 2025-03-04
- DOI
- https://doi.org/10.1186/s40659-025-00594-6
- Citations
- 1
- Primary Topic
- Retinal Development and Disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.81
Funders
- Agencia Nacional de Investigación y Desarrollo