Treatment of non-Hodgkin lymphoma with point-of-care manufactured CAR T cells: a dual institution, phase 1 trial
This clinical trial was funded through University Hospitals Seidman Cancer Center and Washington University School of Medicine Institutional Funds. Correlative analyses were funded in part by the European Union-Next Generation EU-NRRP M6C2-Investment 2.1 Enhancement and strengthening of biomedical research in the NHS (project #PNRR-MAD-2022-12376059), and the Italian Ministry of Health Ricerca Finalizzata 2019 (project #RF-2019-12370243).
Authors
- Boro Dropulić
- David N. Wald
- Kirsten M Boughan
- Brenda Cooper (ORCID: https://orcid.org/0000-0001-9376-9377)
- Paolo F. Caimi (ORCID: https://orcid.org/0000-0003-1436-0464)
- Jane Reese (ORCID: https://orcid.org/0000-0002-0337-5372)
- Rimas J. Orentas (ORCID: https://orcid.org/0000-0002-6310-3467)
- Zachary Jackson (ORCID: https://orcid.org/0000-0003-3655-8279)
- Krishna Goparaju
- Marcos de Lima (ORCID: https://orcid.org/0000-0002-8568-4522)
- Ashish Sharma (ORCID: https://orcid.org/0000-0001-9444-7046)
- Linda Eissenberg (ORCID: https://orcid.org/0000-0002-7905-572X)
- Leland Metheny (ORCID: https://orcid.org/0000-0002-1980-9999)
- Martina Di Trani (ORCID: https://orcid.org/0000-0002-7529-8409)
- Rafick‐Pierre Sékaly (ORCID: https://orcid.org/0000-0002-7816-4828)
- Carmelo Carlo‐Stella (ORCID: https://orcid.org/0000-0003-3144-0124)
- Andrew Worden A.S
- Julie Ritchey
- Emily Craig Zabor (ORCID: https://orcid.org/0000-0002-1402-4498)
- Folashade Otegbeye (ORCID: https://orcid.org/0000-0002-9978-4719)
- John F. DiPersio (ORCID: https://orcid.org/0000-0002-0429-3133)
- Kayla Zamborsky
- Molly Gallogly
- Winfried Krüger
- Benjamin Tomlinson (ORCID: https://orcid.org/0000-0002-2407-0973)
- Dina Schneider (ORCID: https://orcid.org/0000-0001-7130-7374)
- Armin Ghobadi (ORCID: https://orcid.org/0000-0001-8848-8474)
- Sarah Kleinsorge-Block
- Jennifer Schiavone
- Michael J. Kadan
Institutions
- Seattle Children's Hospital (US)
- Cleveland Clinic (US)
- Humanitas University (IT)
- Emory University (US)
- Washington University in St. Louis (US)
- University Hospitals of Cleveland (US)
- The Ohio State University Wexner Medical Center (US)
- Fred Hutch Cancer Center (US)
- Louis Stokes Cleveland VA Medical Center (US)
- Lentigen Technology (United States) (US)
- Capital Caring (US)
- IRCCS Humanitas Research Hospital (IT)
- Case Comprehensive Cancer Center
Publication Details
- Journal
- EClinicalMedicine
- Published
- 2025-03-01
- DOI
- https://doi.org/10.1016/j.eclinm.2025.103138
- Citations
- 4
- Primary Topic
- CAR-T cell therapy research
- Type
- article
- Field-Weighted Citation Impact
- 4.18