The last update on polycystic ovary syndrome(PCOS), diagnosis criteria, and novel treatment

Polycystic Ovary Syndrome (PCOS) is a prevalent reproductive disease influencing 4–20 % of women, often resulting in delayed diagnosis and correlated metabolic issues such as obesity and insulin resistance, impacting their quality of life. Diagnosis is guided according to the Rotterdam criteria, oligo-anovulation, polycystic ovary morphology, and incorporating hyperandrogenism, with Anti-Müllerian hormone as an indicator for ovary morphology. PCOS management necessitates a multifaceted approach, including lifestyle modifications, weight loss strategies, dietary adjustments, and pharmacological interventions. Lifestyle interventions, comprising exercise regimens, dietary modifications, and behavioral strategies, exhibit the potential to enhance metabolic health among PCOS patients. While no singular diet or exercise regimen emerges as superior, the Mediterranean and ketogenic diets have demonstrated favorable effects. Pharmacological interventions, such as combined oral contraceptives, metformin, and clomiphene citrate, assume pivotal roles in regulating menstrual cycles and mitigating hyperandrogenism symptoms. Personalized approaches, tailored to individual responses, are imperative for optimizing outcomes in the management of PCOS.

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Publication Details

Journal
Endocrine and Metabolic Science
Published
2025-03-01
DOI
https://doi.org/10.1016/j.endmts.2025.100228
Citations
29
Primary Topic
Ovarian function and disorders
Type
article
Field-Weighted Citation Impact
49.24
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article

The last update on polycystic ovary syndrome(PCOS), diagnosis criteria, and novel treatment

Majid Banimohammad, Shaghik Barani, Reza Samie, Arghavan Ghafari et al.
29 citations
Endocrine and Metabolic Science
Ovarian function and disorders
49.24
article

The last update on polycystic ovary syndrome(PCOS), diagnosis criteria, and novel treatment

Majid Banimohammad, Shaghik Barani, Reza Samie, Arghavan Ghafari, Malihe Maftoohi, Mohammadamin Eslami Samarin
article en
29 citations

Abstract

Polycystic Ovary Syndrome (PCOS) is a prevalent reproductive disease influencing 4–20 % of women, often resulting in delayed diagnosis and correlated metabolic issues such as obesity and insulin resistance, impacting their quality of life. Diagnosis is guided according to the Rotterdam criteria, oligo-anovulation, polycystic ovary morphology, and incorporating hyperandrogenism, with Anti-Müllerian hormone as an indicator for ovary morphology. PCOS management necessitates a multifaceted approach, including lifestyle modifications, weight loss strategies, dietary adjustments, and pharmacological interventions. Lifestyle interventions, comprising exercise regimens, dietary modifications, and behavioral strategies, exhibit the potential to enhance metabolic health among PCOS patients. While no singular diet or exercise regimen emerges as superior, the Mediterranean and ketogenic diets have demonstrated favorable effects. Pharmacological interventions, such as combined oral contraceptives, metformin, and clomiphene citrate, assume pivotal roles in regulating menstrual cycles and mitigating hyperandrogenism symptoms. Personalized approaches, tailored to individual responses, are imperative for optimizing outcomes in the management of PCOS.

Endocrine and Metabolic ScienceVol. 17
Ahvaz Jundishapur University of Medical Sciences (IR), Iran University of Medical Sciences (IR), Universal Scientific Education and Research Network (IR), Hormozgan University of Medical Sciences (IR), Shahid Beheshti University of Medical Sciences (IR)
Zero hunger
Openalex Percentile: Top 0%
Ovarian function and disorders
49.24
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