Role of Curcumin in Modulating Autophagy for CVD Treatment

This comprehensive review explores the intricate relationship between curcumin and autophagy in the context of Cardiovascular Disease (CVD). It provides a detailed overview of autophagy, its important role in maintaining cellular homeostasis, and its dysregulation in different types of cardiovascular disease, including atherosclerosis, coronary artery disease, and diabetic cardiomyopathy. This review investigates the mechanisms through which curcumin modulates autophagy, highlighting its potential as a therapeutic agent. By discussing the impact of curcumin on CVD, we offer valuable insights into its potential benefits in the prevention and treatment of CVD. Overall, this review highlights the significance of curcumin-mediated autophagy modulation as a promising avenue for addressing the global burden of cardiovascular disease. Keywords: Curcumin, Cardiovascular disease, Autophagy, Coronary artery disease, Cardiomyopathy, Atherosclerosis

Authors

Publication Details

Journal
Journal of Cardiovascular Disorders
Published
2024-10-15
DOI
https://doi.org/10.26420/jcardiovascdisord.2024.1056
Primary Topic
Autophagy in Disease and Therapy
Type
article
Field-Weighted Citation Impact
0.00

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Role of Curcumin in Modulating Autophagy for CVD Treatment

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article en

Abstract

This comprehensive review explores the intricate relationship between curcumin and autophagy in the context of Cardiovascular Disease (CVD). It provides a detailed overview of autophagy, its important role in maintaining cellular homeostasis, and its dysregulation in different types of cardiovascular disease, including atherosclerosis, coronary artery disease, and diabetic cardiomyopathy. This review investigates the mechanisms through which curcumin modulates autophagy, highlighting its potential as a therapeutic agent. By discussing the impact of curcumin on CVD, we offer valuable insights into its potential benefits in the prevention and treatment of CVD. Overall, this review highlights the significance of curcumin-mediated autophagy modulation as a promising avenue for addressing the global burden of cardiovascular disease. Keywords: Curcumin, Cardiovascular disease, Autophagy, Coronary artery disease, Cardiomyopathy, Atherosclerosis

Journal of Cardiovascular Disorders
Mashhad University of Medical Sciences
Openalex Percentile: Top 62%
Autophagy in Disease and Therapy
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