Multitargeted biological actions of polydatin in preventing pseudogout acute attack
PD effectively prevents inflammatory responses to CPP crystals in mice, preserving both articular and muscular structures. Its anti-inflammatory effects are primarily mediated through pathways regulating leukocyte migration and the suppression of pro-inflammatory mediators.
Authors
- Giampietro Ravagnan (ORCID: https://orcid.org/0000-0002-7741-4979)
- Roberto Luisetto
- Francesca Oliviero (ORCID: https://orcid.org/0000-0002-4958-5105)
- Chiara Baggio (ORCID: https://orcid.org/0009-0009-2862-8055)
- Paolo Sfriso (ORCID: https://orcid.org/0000-0001-6432-7174)
- Leonardo Punzi (ORCID: https://orcid.org/0000-0002-8853-516X)
- Andrea Doria (ORCID: https://orcid.org/0000-0003-0548-4983)
- Roberta Ramonda (ORCID: https://orcid.org/0000-0002-9683-8873)
- Gianmaria Pennelli (ORCID: https://orcid.org/0000-0003-0210-165X)
- Paola Galozzi (ORCID: https://orcid.org/0000-0002-8228-2069)
- Vanni Lazzarin
- Amelia Damasco (ORCID: https://orcid.org/0009-0008-7091-0882)
Institutions
- University of Padua (IT)
- Istituto di Farmacologia Traslazionale (IT)
- National Research Council (IT)
Publication Details
- Journal
- Frontiers in Molecular Biosciences
- Published
- 2025-02-27
- DOI
- https://doi.org/10.3389/fmolb.2025.1553912
- Citations
- 1
- Primary Topic
- Bioactive natural compounds
- Type
- article
- Field-Weighted Citation Impact
- 0.81
Funders
- Università degli Studi di Padova