Increased PCSK9 associated with cIMT in AS: A useful marker for subclinical atherosclerosis in patients with ankylosing spondylitis
Our study showed that serum PCSK9 levels in patients with AS were higher than that in healthy individuals and were associated with SA and arterial plaque formation. In the light of these findings, PCSK9 may accelerate SA and carotid plaque formation in patients with AS, regardless of the LDL cholesterol level. There may be no relationship between PCSK9 levels and disease activity in patients with AS.
Authors
- Ahmet Karakoyun (ORCID: https://orcid.org/0000-0001-8288-9744)
- Mustafa Oğul (ORCID: https://orcid.org/0000-0002-8044-7616)
- Cengiz Kadıyoran (ORCID: https://orcid.org/0000-0002-7173-3530)
- Pınar Diydem Yılmaz (ORCID: https://orcid.org/0000-0002-8519-5382)
- Mevlüt Hakan Göktepe (ORCID: https://orcid.org/0000-0003-1711-5157)
- Adem Küçük (ORCID: https://orcid.org/0000-0001-8028-1671)
- Yasemin Akkubak
Institutions
- Aksaray University (TR)
- Konya Numune Hastanesi (TR)
- Necmettin Erbakan University (TR)
Publication Details
- Journal
- Archives of Rheumatology
- Published
- 2024-12-31
- DOI
- https://doi.org/10.46497/archrheumatol.2024.10625
- Citations
- 1
- Primary Topic
- Lipoproteins and Cardiovascular Health
- Type
- article
- Field-Weighted Citation Impact
- 0.57