Cardiac osteochondrolipoma in a cheetah

A 13-y-old captive female cheetah (<i>Acinonyx jubatus</i>) succumbed following the acute onset of respiratory distress. Autopsy revealed bacterial bronchopneumonia as the primary cause of death. Additionally, splenic myelolipomas and systemic amyloidosis were identified postmortem. Interestingly, a solitary, firm nodule was found in the right atrial wall, consisting histologically of mature adipocytes with partial osseous and cartilaginous differentiation, consistent with osteochondrolipoma. Hepatic congestion suggested right heart failure. Although the direct impact of the cardiac mass on heart function remains unclear, its potential contribution to the fatal outcome cannot be discounted. To our knowledge, cardiac osteochondrolipoma has not been reported previously in cheetahs or other animals.

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Publication Details

Journal
Journal of Veterinary Diagnostic Investigation
Published
2025-02-28
DOI
https://doi.org/10.1177/10406387251322763
Primary Topic
Peroxisome Proliferator-Activated Receptors
Type
article
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article

Cardiac osteochondrolipoma in a cheetah

Soong-Hee Youn, Jeong-Seop Oh, Ki-Yong Shin, Dawoon Chung et al.
Journal of Veterinary Diagnostic Investigation
Peroxisome Proliferator-Activated Receptors
article

Cardiac osteochondrolipoma in a cheetah

Soong-Hee Youn, Jeong-Seop Oh, Ki-Yong Shin, Dawoon Chung, Eunjung Jung, Nayoung Lee, Dae-Yong Kim
article en

Abstract

A 13-y-old captive female cheetah (<i>Acinonyx jubatus</i>) succumbed following the acute onset of respiratory distress. Autopsy revealed bacterial bronchopneumonia as the primary cause of death. Additionally, splenic myelolipomas and systemic amyloidosis were identified postmortem. Interestingly, a solitary, firm nodule was found in the right atrial wall, consisting histologically of mature adipocytes with partial osseous and cartilaginous differentiation, consistent with osteochondrolipoma. Hepatic congestion suggested right heart failure. Although the direct impact of the cardiac mass on heart function remains unclear, its potential contribution to the fatal outcome cannot be discounted. To our knowledge, cardiac osteochondrolipoma has not been reported previously in cheetahs or other animals.

Journal of Veterinary Diagnostic InvestigationVol. 37(3)
Seoul National University (KR)
Good health and well-being
Openalex Percentile: Top 96%
Peroxisome Proliferator-Activated Receptors
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