Allopregnanolone as an Adjunct Therapy to Midazolam is More Effective Than Midazolam Alone in Suppressing Soman‐Induced Status Epilepticus in Male Rats
Treatment with midazolam followed by ALLO was more effective than 2 doses of midazolam in suppressing benzodiazepine-refractory, soman-induced SE, and in mitigating its acute neuropathological consequences.
Authors
- Michael A. Rogawski (ORCID: https://orcid.org/0000-0002-3296-8193)
- Danielle Harvey (ORCID: https://orcid.org/0000-0002-5367-0951)
- Pamela J. Lein (ORCID: https://orcid.org/0000-0001-7665-7584)
- Naomi Saito (ORCID: https://orcid.org/0000-0003-4069-3721)
- Peter M. Andrew (ORCID: https://orcid.org/0000-0001-9395-381X)
- Ashish Dhir (ORCID: https://orcid.org/0000-0001-5746-7312)
- Kyle E. Berger
- Hilary S. McCarren
- Jeremy A. MacMahon (ORCID: https://orcid.org/0000-0002-4504-4571)
- Julia E. Morgan
- Xiuzhen Liu (ORCID: https://orcid.org/0000-0002-2298-1757)
Institutions
- United States Army Medical Research Institute of Infectious Diseases (US)
- University of California, Davis (US)
Publication Details
- Journal
- CNS Neuroscience & Therapeutics
- Published
- 2025-02-28
- DOI
- https://doi.org/10.1111/cns.70215
- Citations
- 2
- Primary Topic
- Neuroscience and Neuropharmacology Research
- Type
- article
- Field-Weighted Citation Impact
- 1.82
Funders
- U.S. Department of Energy
- National Institute of Neurological Disorders and Stroke
- Eunice Kennedy Shriver National Institute of Child Health and Human Development