Coagulation Factors and White Matter Hyperintensities in Middle‐Aged Women With and Without Migraine and Ischemic Stroke
In women with both stroke and migraine, VWF:Ag levels were increased, while fibrinogen, FIX, and FXI:C were not. This suggests that endothelial activation might be more relevant than a procoagulant state alone in the pathophysiology of ischemic stroke in women with migraine. Coagulation factors did not seem to be related to WMH volume, suggesting other mechanisms may be involved in their development.
Authors
- Ghislaine Holswilder (ORCID: https://orcid.org/0000-0002-9788-4345)
- Nyika D. Kruyt (ORCID: https://orcid.org/0000-0002-2320-0932)
- Annelise E. Wilms (ORCID: https://orcid.org/0000-0002-1789-1140)
- Mark C. Kruit (ORCID: https://orcid.org/0000-0002-4319-834X)
- Suzanne C. Cannegieter (ORCID: https://orcid.org/0000-0003-4707-2303)
- Thijs W. van Harten (ORCID: https://orcid.org/0000-0002-3408-9379)
- Bart J.M. van Vlijmen (ORCID: https://orcid.org/0000-0003-0208-6453)
- Gisela M. Terwindt (ORCID: https://orcid.org/0000-0003-3140-6882)
- Marieke J.H. Wermer (ORCID: https://orcid.org/0000-0002-6838-9521)
- Mariam Ali (ORCID: https://orcid.org/0000-0003-3409-7835)
- Katie M. Linstra (ORCID: https://orcid.org/0000-0001-8338-8597)
- Hendrikus J. A. van Os (ORCID: https://orcid.org/0000-0002-8911-8608)
- Nelleke van der Weerd (ORCID: https://orcid.org/0000-0001-7700-274X)
- Bob Siegerink (ORCID: https://orcid.org/0000-0002-8454-9142)
- Antoinette MaassenVanDenBrink (ORCID: https://orcid.org/0000-0001-7176-126X)
- L. Renee Ruhaak (ORCID: https://orcid.org/0000-0003-3737-3807)
Institutions
- University Medical Center Groningen (NL)
- Harvard University (US)
- Leiden University Medical Center (NL)
- Massachusetts General Hospital (US)
Publication Details
- Journal
- European Journal of Neurology
- Published
- 2025-02-28
- DOI
- https://doi.org/10.1111/ene.70063
- Citations
- 2
- Primary Topic
- Migraine and Headache Studies
- Type
- article
- Field-Weighted Citation Impact
- 2.94
Funders
- ZonMw