Möbius Syndrome With Possible Poland Syndrome Overlap: A Case Report

Möbius syndrome (MBS) is a rare congenital neurological disorder. It is primarily characterized by underdevelopment of the facial and abducens nerves, leading to facial paralysis and limited eye movement. Musculoskeletal anomalies and neurodevelopmental challenges add to its complexity. Neuroimaging, particularly magnetic resonance imaging (MRI), often shows brainstem hypoplasia and flattening of the fourth ventricle floor. This case report describes a six-year-old child with facial asymmetry, incomplete eye closure, and abnormal head posture. These features suggest facial and abducens nerve palsy, both key signs of Möbius syndrome. The child also had pectoral muscle atrophy and nipple deformity, raising the possibility of Poland syndrome. This condition has occasionally been reported alongside Möbius syndrome. Clinical evaluations were consistent with these findings. Genetic testing was not performed but could provide further insights. The overlap between Möbius and Poland syndrome highlights the complexity of these disorders. A multidisciplinary approach is essential for management, and an early and thorough clinical evaluation is key to timely diagnosis and intervention.