The “Wearing Off” Phenomenon for Rasagiline, Entacapone, Carbidopa, and Levodopa in the Setting of Parkinson’s Disease
This case highlights the importance of accurate dosage and vigilant supervision of Parkinson's disease medications' "wearing off" phenomenon. The patient's varying reaction to changes in medication and the subsequent appearance of psychiatric symptoms highlights the need for an individualized approach to managing Parkinson's disease. Collectively, these symptoms suggest that clinicians should consider the possibility of non-linear connections between dopaminergic therapy and symptom control. To effectively address the intricate relationship between motor symptoms and psychiatric manifestations, it is imperative to implement a multidisciplinary team approach in future management. This approach would involve closely monitoring and adapting treatment strategies.
Authors
- Terry Taewoong Um (ORCID: https://orcid.org/0000-0002-9331-2016)
- R. L. Cromwell
Institutions
- Florida Department of Citrus (US)
Publication Details
- Journal
- HCA Healthcare Journal of Medicine
- Published
- 2025-02-28
- DOI
- https://doi.org/10.36518/2689-0216.1718
- Citations
- 1
- Primary Topic
- Parkinson's Disease Mechanisms and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.39