Evaluating nebulisation and nasal irrigation efficiency in post-operative chronic rhinosinusitis patients through computational fluid dynamics simulation

These findings emphasise the importance of adapting drug delivery strategies to specific surgical and anatomical factors. Tailored post-operative protocols may enhance outcomes in CRS, potentially improving patient comfort and compliance, and reducing recurrence rates. Further investigations are warranted to precisely quantify the liquid layer thickness remaining after irrigation, particularly as head movements can result in medication flowing back from sinuses into the nasal cavity.

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Publication Details

Journal
Computer Methods and Programs in Biomedicine
Published
2025-03-02
DOI
https://doi.org/10.1016/j.cmpb.2025.108697
Citations
7
Primary Topic
Inhalation and Respiratory Drug Delivery
Type
article
Field-Weighted Citation Impact
10.63
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article

Evaluating nebulisation and nasal irrigation efficiency in post-operative chronic rhinosinusitis patients through computational fluid dynamics simulation

Alkis J. Psaltis, Sarah Vreugde, Kiao Inthavong, Peter‐John Wormald et al.
7 citations
Computer Methods and Programs in Biomedicine
Inhalation and Respiratory Drug Delivery
10.63
article

Evaluating nebulisation and nasal irrigation efficiency in post-operative chronic rhinosinusitis patients through computational fluid dynamics simulation

Alkis J. Psaltis, Sarah Vreugde, Kiao Inthavong, Peter‐John Wormald, O. Pourmehran, Kavan Zarei, Yidan Shang
article en
7 citations

Abstract

These findings emphasise the importance of adapting drug delivery strategies to specific surgical and anatomical factors. Tailored post-operative protocols may enhance outcomes in CRS, potentially improving patient comfort and compliance, and reducing recurrence rates. Further investigations are warranted to precisely quantify the liquid layer thickness remaining after irrigation, particularly as head movements can result in medication flowing back from sinuses into the nasal cavity.

Computer Methods and Programs in BiomedicineVol. 264
Shanghai University of Engineering Science (CN), The University of Adelaide (AU), RMIT University (AU)
Clean water and sanitation
Openalex Percentile: Top 2%
Inhalation and Respiratory Drug Delivery
10.63
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Evaluating nebulisation and nasal irrigation efficiency in post-operative chronic rhinosinusitis patients through computational fluid dynamics simulation — Alkis J. Psaltis, Sarah Vreugde, et al. · Computer Methods and Programs in Biomedicine (2025) | TGRS Research Map | TGRS