Functional brain connectivity in early adolescence after hypothermia-treated neonatal hypoxic-ischemic encephalopathy

Neonatal hypoxic-ischemic encephalopathy (HIE) could not be associated with alterations in functional connectivity in this cohort of adolescent children. Findings of aberrant connectivity identified in two functional networks were no longer significant after correction for multiple comparisons. Larger, multi-center studies are needed to understand whether network abnormalities persist long term and are related to outcomes in neonatal HIE.

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Publication Details

Journal
Pediatric Research
Published
2025-03-02
DOI
https://doi.org/10.1038/s41390-025-03951-z
Citations
3
Primary Topic
Neonatal and fetal brain pathology
Type
article
Field-Weighted Citation Impact
10.48

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article

Functional brain connectivity in early adolescence after hypothermia-treated neonatal hypoxic-ischemic encephalopathy

Peter Fransson, Mats Blennow, Gustaf Håkansson, Ulrika Ådén et al.
3 citations
Pediatric Research
Neonatal and fetal brain pathology
10.48
article

Functional brain connectivity in early adolescence after hypothermia-treated neonatal hypoxic-ischemic encephalopathy

Peter Fransson, Mats Blennow, Gustaf Håkansson, Ulrika Ådén, Katarina Robertsson Grossmann
article en
3 citations

Abstract

Neonatal hypoxic-ischemic encephalopathy (HIE) could not be associated with alterations in functional connectivity in this cohort of adolescent children. Findings of aberrant connectivity identified in two functional networks were no longer significant after correction for multiple comparisons. Larger, multi-center studies are needed to understand whether network abnormalities persist long term and are related to outcomes in neonatal HIE.

Pediatric ResearchVol. 98(5)
Linköping University (SE), Karolinska University Hospital (SE), Karolinska Institutet (SE)
Stiftelsen Promobilia, Kempe Foundation, Karolinska Institutet, Norrbacka-Eugeniastiftelsen, Stiftelsen Sven Jerrings Fond, Stiftelsen Kempe-Carlgrenska Fonden
Openalex Percentile: Top 3%
Neonatal and fetal brain pathology
10.48
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Functional brain connectivity in early adolescence after hypothermia-treated neonatal hypoxic-ischemic encephalopathy — Peter Fransson, Mats Blennow, et al. · Pediatric Research (2025) | TGRS Research Map | TGRS