Effective compound combination of Bufei Yishen formula ameliorates PM2.5-induced COPD by inhibiting mitochondrial oxidative stress through SIRT3-mediated FOXO3 deacetylation
This study reveals a previously unrecognized mechanism by which ECC acts as an agonist of SIRT3, offering potential therapeutic benefits for patients with COPD who are exposed to PM2.5.
Authors
- Yan Dong (ORCID: https://orcid.org/0000-0003-3553-1488)
- Jing Wang (ORCID: https://orcid.org/0000-0002-7501-8702)
- Tiantian Liu (ORCID: https://orcid.org/0009-0008-7241-281X)
- Jiansheng Li (ORCID: https://orcid.org/0000-0002-6485-2371)
- Huiyu Yue
Institutions
- First Affiliated Hospital of Henan University (CN)
Publication Details
- Journal
- Phytomedicine
- Published
- 2025-03-02
- DOI
- https://doi.org/10.1016/j.phymed.2025.156568
- Citations
- 6
- Primary Topic
- Sirtuins and Resveratrol in Medicine
- Type
- article
- Field-Weighted Citation Impact
- 7.34