Design and Characterization of Ricin Based Immunotoxins Against EPHA2 Receptor for Breast Cancer Therapy: An In-Silico Study
Based on these observations, it is reasonable to conclude that both designed immunotoxins could serve as suitable immunotoxins; however, construct 2 exhibits more promising properties. Given these results, these immunotoxins could be used in empirical studies to treat breast cancer in vitro or in vivo.
Authors
- Shohreh Zare Karizi (ORCID: https://orcid.org/0000-0002-0305-8588)
- Sedigheh Arbabian (ORCID: https://orcid.org/0000-0002-1212-003X)
- Maryam Bikhof Torbati (ORCID: https://orcid.org/0000-0001-8784-8589)
- Atefeh Faraz
- Jafar Amani
Institutions
- Baqiyatallah University of Medical Sciences (IR)
- Islamic Azad University North Tehran Branch (IR)
- Islamic Azad University of Varamin (IR)
- Islamic Azad University Shahr-e-Rey (IR)
Publication Details
- Journal
- Iranian journal of pharmaceutical research
- Published
- 2025-02-22
- DOI
- https://doi.org/10.5812/ijpr-151574
- Primary Topic
- Toxin Mechanisms and Immunotoxins
- Type
- article
- Field-Weighted Citation Impact
- 0.00