In silico and <i>in vivo</i> evaluation of erucic acid against pentylenetetrazole-induced seizures in mice by modulating oxidative stress, neurotransmitters and neuroinflammation markers
Erucic acid may be an effective natural compound in PTZ-induced seizures in mice by restoring neurotransmitters, oxidative stress and neuroinflammatory mediators. It could prove to be a better alternative in the treatment of epilepsy.
Authors
- Omar Awad Alsaidan (ORCID: https://orcid.org/0000-0002-2848-2932)
- Muhammad Afzal (ORCID: https://orcid.org/0000-0001-9530-1356)
- Sami I. Alzarea (ORCID: https://orcid.org/0000-0003-4007-4023)
- Ehssan Moglad (ORCID: https://orcid.org/0000-0002-1076-9740)
- Nadeem Sayyed (ORCID: https://orcid.org/0000-0003-0517-4934)
- Abdulaziz Ibrahim Alzarea (ORCID: https://orcid.org/0000-0003-0604-6299)
- Hassan H. Alhassan (ORCID: https://orcid.org/0000-0002-7174-9831)
- Imran Kazmi (ORCID: https://orcid.org/0000-0003-1881-5219)
Institutions
- Prince Sattam Bin Abdulaziz University (SA)
- King Abdulaziz University (SA)
- Jouf University (SA)
- Glocal University (IN)
- Batterjee Medical College
Publication Details
- Journal
- Nutritional Neuroscience
- Published
- 2025-02-28
- DOI
- https://doi.org/10.1080/1028415x.2025.2463677
- Citations
- 1
- Primary Topic
- Neuroscience and Neuropharmacology Research
- Type
- article
- Field-Weighted Citation Impact
- 0.91