Baseline ophthalmic findings and complications in pediatric patients treated with MEK inhibitors
The majority of children started on MEK inhibitors had baseline eye abnormalities due to ocular or visual pathway involvement of neurological tumors. Ophthalmic side effects of MEK inhibitors occurred in 7% of children. Additional studies are required to formulate screening guidelines for the pediatric population.
Authors
- Jennifer L. Rossen (ORCID: https://orcid.org/0000-0002-9742-8868)
- Vikisha Hazariwala
- Angela J. Waanders (ORCID: https://orcid.org/0000-0002-0571-2889)
- Brenda L. Bohnsack (ORCID: https://orcid.org/0000-0001-8961-6343)
- Janice Lasky-Zeid
Institutions
- Lurie Children's Hospital (US)
Publication Details
- Journal
- Journal of American Association for Pediatric Ophthalmology and Strabismus
- Published
- 2025-03-01
- DOI
- https://doi.org/10.1016/j.jaapos.2025.104157
- Citations
- 2
- Primary Topic
- Ocular Oncology and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 3.41