A privacy-preserving dependable deep federated learning model for identifying new infections from genome sequences

The traditional molecular-based identification (TMID) technique of new infections from genome sequences (GSs) has made significant contributions so far. However, due to the sensitive nature of the medical data, the TMID technique of transferring the patient's data to the central machine or server may create severe privacy and security issues. In recent years, the progression of deep federated learning (DFL) and its remarkable success in many domains has guided as a potential solution in this field. Therefore, we proposed a dependable and privacy-preserving DFL-based identification model of new infections from GSs. The unique contributions include automatic effective feature selection, which is best suited for identifying new infections, designing a dependable and privacy-preserving DFL-based LeNet model, and evaluating real-world data. To this end, a comprehensive experimental performance evaluation has been conducted. Our proposed model has an overall accuracy of 99.12% after independently and identically distributing the dataset among six clients. Moreover, the proposed model has a precision of 98.23%, recall of 98.04%, f1-score of 96.24%, Cohen's kappa of 83.94%, and ROC AUC of 98.24% for the same configuration, which is a noticeable improvement when compared to the other benchmark models. The proposed dependable model, along with empirical results, is encouraging enough to recognize as an alternative for identifying new infections from other virus strains by ensuring proper privacy and security of patients' data.

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Publication Details

Journal
Scientific Reports
Published
2025-03-01
DOI
https://doi.org/10.1038/s41598-025-89612-x
Citations
2
Primary Topic
COVID-19 diagnosis using AI
Type
article
Field-Weighted Citation Impact
2.72
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article

A privacy-preserving dependable deep federated learning model for identifying new infections from genome sequences

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2 citations
Scientific Reports
COVID-19 diagnosis using AI
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article

A privacy-preserving dependable deep federated learning model for identifying new infections from genome sequences

Muhammad Shahin Uddin, Mohammad Ali Moni, Francis M. Bui, Lway Faisal Abdulrazak, Sk. Tanzir Mehedi, Li Chen, Fahad Ahmed Al-Zahrani
article en
2 citations

Abstract

The traditional molecular-based identification (TMID) technique of new infections from genome sequences (GSs) has made significant contributions so far. However, due to the sensitive nature of the medical data, the TMID technique of transferring the patient's data to the central machine or server may create severe privacy and security issues. In recent years, the progression of deep federated learning (DFL) and its remarkable success in many domains has guided as a potential solution in this field. Therefore, we proposed a dependable and privacy-preserving DFL-based identification model of new infections from GSs. The unique contributions include automatic effective feature selection, which is best suited for identifying new infections, designing a dependable and privacy-preserving DFL-based LeNet model, and evaluating real-world data. To this end, a comprehensive experimental performance evaluation has been conducted. Our proposed model has an overall accuracy of 99.12% after independently and identically distributing the dataset among six clients. Moreover, the proposed model has a precision of 98.23%, recall of 98.04%, f1-score of 96.24%, Cohen's kappa of 83.94%, and ROC AUC of 98.24% for the same configuration, which is a noticeable improvement when compared to the other benchmark models. The proposed dependable model, along with empirical results, is encouraging enough to recognize as an alternative for identifying new infections from other virus strains by ensuring proper privacy and security of patients' data.

Scientific ReportsVol. 15(1)
Cihan University-Erbil (IQ), Charles Sturt University (AU), Umm al-Qura University (SA), Daffodil International University (BD), University of Saskatchewan (CA), Mawlana Bhashani Science and Technology University (BD), Middle Technical University (IQ), Université Bourgogne Franche-Comté (FR), Cihan University Sulaimaniya
Openalex Percentile: Top 12%
COVID-19 diagnosis using AI
2.72
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