Therapeutic Potential of TPT-260 in Ischemic Stroke: An Investigation Into Its Anti-Inflammatory Effects and Impact on Microglial Activation
TPT-260 attenuated M1 microglia via repression of NF-κB signaling, thus preventing neuroinflammation and neuronal injuries in stroke model mice.
Authors
- Zhidong Huang (ORCID: https://orcid.org/0000-0002-5267-5769)
- Xu Qian (ORCID: https://orcid.org/0000-0001-5539-1983)
- Xiaoming Guo (ORCID: https://orcid.org/0000-0003-3840-5743)
- Jun Qian (ORCID: https://orcid.org/0000-0002-7288-6942)
Institutions
- Nantong University (CN)
- Affiliated Hospital of Nantong University (CN)
- Second Affiliated Hospital of Nantong University
Publication Details
- Journal
- Journal of Inflammation Research
- Published
- 2025-03-01
- DOI
- https://doi.org/10.2147/jir.s497030
- Citations
- 2
- Primary Topic
- Neuroinflammation and Neurodegeneration Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 1.68