Association between cancer-associated fibroblasts and prognosis of neoadjuvant chemoradiotherapy in esophageal squamous cell carcinoma: a bioinformatics analysis based on single-cell RNA sequencing
Our findings highlight the dynamic alterations in the post-NCRT ESCC microenvironment and provide a foundation for the development of personalized treatment and immunotherapeutic approaches. Future studies are warranted to further validate these findings and explore their clinical implications.
Authors
- Zhao Huang (ORCID: https://orcid.org/0000-0001-9994-2070)
- Zhiqiang Zou (ORCID: https://orcid.org/0000-0002-4349-3242)
- Yang Xu (ORCID: https://orcid.org/0000-0002-8786-1318)
- Chuan Gao (ORCID: https://orcid.org/0000-0003-0248-1269)
- Bingmei Qiu (ORCID: https://orcid.org/0009-0006-4706-8151)
- Yi Shen (ORCID: https://orcid.org/0000-0001-5683-2090)
- Zhuangzhuang Cong
- Kang Wang (ORCID: https://orcid.org/0000-0002-4963-2979)
- Nan Yang (ORCID: https://orcid.org/0009-0000-5926-3663)
- Jing Luo
- Li Hu
Institutions
- Nanjing General Hospital of Nanjing Military Command (CN)
- 82th Hospital of Pla (CN)
- Nanjing University (CN)
Publication Details
- Journal
- Cancer Cell International
- Published
- 2025-03-01
- DOI
- https://doi.org/10.1186/s12935-025-03709-x
- Citations
- 5
- Primary Topic
- Esophageal Cancer Research and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 10.03