Hepatic immune environment differences among common mouse strains in models of MASH and liver cancer
Our immune cell profiling study revealed that the liver immune environment can be quite different among common mouse strains both under healthy and pathologic states, such as steatohepatitis or neoplastic processes. Our results serve as a data resource for studies investigating liver immunology and provide valuable insights for the design of studies on various immune cells in the livers of mice.
Authors
- Jonathan Qi (ORCID: https://orcid.org/0000-0001-9871-5386)
- Yuta Myojin (ORCID: https://orcid.org/0000-0003-0360-9703)
- Francisco Rodríguez-Matos (ORCID: https://orcid.org/0000-0002-8469-477X)
- Patrick Huang (ORCID: https://orcid.org/0000-0003-4833-8134)
- Rajiv Trehan (ORCID: https://orcid.org/0000-0002-2819-0534)
- Tim F. Greten (ORCID: https://orcid.org/0000-0002-0806-2535)
- Xiao Bin Zhu
- Chi Ma (ORCID: https://orcid.org/0000-0002-4171-0813)
Institutions
- National Institutes of Health (US)
- National Cancer Institute (US)
- Center for Cancer Research (US)
Publication Details
- Journal
- JHEP Reports
- Published
- 2025-03-01
- DOI
- https://doi.org/10.1016/j.jhepr.2025.101380
- Citations
- 1
- Primary Topic
- Liver Disease Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 1.35
Funders
- Emory University
- National Institutes of Health
- National Cancer Institute