Inhibition of circALPK2 enhances proliferation and therapeutic potential of human pluripotent stem cell-derived cardiomyocytes in myocardial infarction
Our study identifies the circALPK2/miR-9/GSK3B axis as a novel target for promoting cardiomyocyte proliferation and enhancing cardiac regeneration.
Authors
- Dandan Zhao (ORCID: https://orcid.org/0000-0001-5194-750X)
- Jun‐Ming Tang (ORCID: https://orcid.org/0000-0002-1591-7626)
- Hao Fan (ORCID: https://orcid.org/0000-0002-4582-7250)
- Miao Yu (ORCID: https://orcid.org/0000-0001-8608-8354)
- Shijun Hu (ORCID: https://orcid.org/0000-0002-0068-8429)
- Yingjiong Lin (ORCID: https://orcid.org/0000-0003-3328-6925)
- Xinglong Han
- Jingjing Li (ORCID: https://orcid.org/0000-0002-2882-2474)
- Yuan Li (ORCID: https://orcid.org/0000-0003-0438-7794)
- Xue Jiang
- Hongchun Wu
Institutions
- Hubei University of Medicine (CN)
- Soochow University (CN)
- First Affiliated Hospital of Soochow University (CN)
Publication Details
- Journal
- Stem Cell Research & Therapy
- Published
- 2025-03-01
- DOI
- https://doi.org/10.1186/s13287-025-04230-8
- Citations
- 2
- Primary Topic
- Circular RNAs in diseases
- Type
- article
- Field-Weighted Citation Impact
- 1.61