Evaluation of a comprehensive set of normal tissue complication probability models for patients with head and neck cancer in an international cohort
Despite differences between the CITOR development and this evaluation cohort, including use of different side-effect scoring systems, most models exhibited moderate-to-high performance. This demonstrated that the dose-effect relations were generalizable. Therefore, this study supports further integration of these NTCP models in clinical practice.
Authors
- Johannes A. Langendijk (ORCID: https://orcid.org/0000-0003-1083-372X)
- Hans Paul van der Laan
- Nanna M. Sijtsema
- A. van der Schaaf (ORCID: https://orcid.org/0000-0003-4067-7975)
- Lisanne V. van Dijk (ORCID: https://orcid.org/0000-0002-9515-5616)
- Katherine A. Hutcheson (ORCID: https://orcid.org/0000-0003-3710-5706)
- L. Van den Bosch (ORCID: https://orcid.org/0000-0002-0573-7517)
- Clifton D. Fuller (ORCID: https://orcid.org/0000-0002-5264-3994)
- Hung Chu (ORCID: https://orcid.org/0000-0002-9531-8980)
- R.J.H.M. Steenbakkers
- Maria I. van Rijn–Dekker (ORCID: https://orcid.org/0000-0002-2803-8997)
- Kylie Keijzer (ORCID: https://orcid.org/0000-0002-8348-0438)
- Peter van Luijk (ORCID: https://orcid.org/0000-0001-7959-1234)
- Jolien Heukelom (ORCID: https://orcid.org/0000-0001-8042-5401)
- Amy C. Moreno (ORCID: https://orcid.org/0000-0001-6762-6807)
- Suzanne P.M. de Vette (ORCID: https://orcid.org/0000-0003-3243-2898)
- Yan Li (ORCID: https://orcid.org/0000-0002-8579-3446)
- Mark L. Frederiks
- Hendrike Neh
Institutions
- University Medical Center Groningen (NL)
- The University of Texas MD Anderson Cancer Center (US)
- Maastro Clinic (NL)
Publication Details
- Journal
- Oral Oncology
- Published
- 2025-03-01
- DOI
- https://doi.org/10.1016/j.oraloncology.2025.107224
- Citations
- 10
- Primary Topic
- Head and Neck Cancer Studies
- Type
- article
- Field-Weighted Citation Impact
- 18.48