Macroscopic T-Wave Alternans: Unusual Presentation in a Cirrhotic Patient

T-wave alternans (TWA), also known as repolarization alterations, refers to the alternating pattern observed in the ST segment, T wave, and U wave. Macroscopic TWA (MTWA) has been observed in patients with various conditions, such as ischemia, electrolyte imbalances, long QT syndrome, and transitions from tachycardia to a normal rhythm. Its recognition is of utmost importance as it serves as a red flag for potentially life-threatening cardiac arrhythmias. Prompt treatment is crucial in order to prevent cardiac arrest and its complications. Patients who exhibit MTWA should be promptly treated with intravenous magnesium sulfate, as magnesium deficiency can contribute to arrhythmias. Additionally, efforts should be made to identify and address any reversible causes that may be contributing to the MTWA. Timely intervention is key to achieving the best possible outcome for patients with MTWA.

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Publication Details

Journal
Cureus
Published
2025-02-28
DOI
https://doi.org/10.7759/cureus.79840
Citations
1
Primary Topic
Cardiac electrophysiology and arrhythmias
Type
article
Field-Weighted Citation Impact
1.39
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article

Macroscopic T-Wave Alternans: Unusual Presentation in a Cirrhotic Patient

Deepa Soodi, Param Sharma, Vinod Kumar Reddy Cirra
1 citations
Cureus
Cardiac electrophysiology and arrhythmias
1.39
article

Macroscopic T-Wave Alternans: Unusual Presentation in a Cirrhotic Patient

Deepa Soodi, Param Sharma, Vinod Kumar Reddy Cirra
article en
1 citations

Abstract

T-wave alternans (TWA), also known as repolarization alterations, refers to the alternating pattern observed in the ST segment, T wave, and U wave. Macroscopic TWA (MTWA) has been observed in patients with various conditions, such as ischemia, electrolyte imbalances, long QT syndrome, and transitions from tachycardia to a normal rhythm. Its recognition is of utmost importance as it serves as a red flag for potentially life-threatening cardiac arrhythmias. Prompt treatment is crucial in order to prevent cardiac arrest and its complications. Patients who exhibit MTWA should be promptly treated with intravenous magnesium sulfate, as magnesium deficiency can contribute to arrhythmias. Additionally, efforts should be made to identify and address any reversible causes that may be contributing to the MTWA. Timely intervention is key to achieving the best possible outcome for patients with MTWA.

CureusVol. 17(2)
Deccan College of Medical Sciences (IN)
Openalex Percentile: Top 22%
Cardiac electrophysiology and arrhythmias
1.39
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Macroscopic T-Wave Alternans: Unusual Presentation in a Cirrhotic Patient — Deepa Soodi, Param Sharma, et al. · Cureus (2025) | TGRS Research Map | TGRS