The Diagnostic Value of Interleukin‐2 and Interferon‐γ Induced by Fusion Protein (<scp>ESAT</scp>‐6/<scp>CFP</scp>‐10/Rv1985c) for Active <i>Mycobacterium tuberculosis</i> Infection
This study demonstrated that IL-2 and IFN-γ release assays induced by the fusion protein (ESAT-6/CFP-10/Rv1985c) were valuable for distinguishing ATB from non-ATB subjects, with IL-2 exhibiting higher specificity and IFN-γ demonstrating higher sensitivity.
Authors
- Runqing Li (ORCID: https://orcid.org/0000-0003-3139-2871)
- Pan Xiong (ORCID: https://orcid.org/0000-0001-6381-6291)
- Yujie Wang (ORCID: https://orcid.org/0000-0002-7299-875X)
- Wei Qian (ORCID: https://orcid.org/0000-0001-7734-7393)
- Zhipeng Zhao
- Xiu-Ying Zhao (ORCID: https://orcid.org/0000-0001-5486-2480)
- Xiaochen Li (ORCID: https://orcid.org/0009-0002-9602-7795)
- Minggui Lin
Institutions
- Beijing Tsinghua Chang Gung Hospital (CN)
- Tsinghua University (CN)
Publication Details
- Journal
- Journal of Clinical Laboratory Analysis
- Published
- 2025-02-28
- DOI
- https://doi.org/10.1002/jcla.70010
- Citations
- 4
- Primary Topic
- Tuberculosis Research and Epidemiology
- Type
- article
- Field-Weighted Citation Impact
- 5.58