Ethanol causes rapid decreases in the hepatic retinoid levels shaping the early steps of alcohol‐associated liver disease
This work reveals that acute and short-term exposures to EtOH disrupt retinoid homeostasis, identifying key events in the early pathogenesis of ALD.
Authors
- Steven S. Gross (ORCID: https://orcid.org/0000-0001-8029-2338)
- Megan R. McMullen (ORCID: https://orcid.org/0009-0007-6020-7125)
- Xiao‐Han Tang (ORCID: https://orcid.org/0000-0002-2328-5868)
- Gene R. Pesola (ORCID: https://orcid.org/0000-0002-3909-8039)
- Laura E. Nagy (ORCID: https://orcid.org/0000-0002-0580-2809)
- M. Melis (ORCID: https://orcid.org/0009-0005-2565-2720)
- Robert E. Schwartz (ORCID: https://orcid.org/0000-0002-5417-5995)
- Lorraine J. Gudas (ORCID: https://orcid.org/0000-0003-3115-4777)
- Christine Lim (ORCID: https://orcid.org/0000-0002-5169-6672)
- Shireen Chikara
- Steven E. Trasino (ORCID: https://orcid.org/0000-0003-1297-3582)
- Sergey Tsoy
- Qiuying Chen (ORCID: https://orcid.org/0000-0001-5909-3959)
- Dawson Miller
Institutions
- Cleveland Clinic (US)
- City University of New York (US)
- Cornell University (US)
- Hunter College (US)
- Weill Cornell Medicine (US)
Publication Details
- Journal
- Alcohol Clinical and Experimental Research
- Published
- 2025-02-27
- DOI
- https://doi.org/10.1111/acer.70011
- Primary Topic
- Liver Disease Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Institute on Alcohol Abuse and Alcoholism
- National Institute of Diabetes and Digestive and Kidney Diseases